Description

(R)-2-((3-(Trifluoromethyl)Phenoxy)Methyl)Oxirane is a high-value chiral epoxide building block, distinguished by its trifluoromethylphenoxy moiety. This compound is critical for introducing chirality and fluorinated aromatic character into advanced molecular architectures, enhancing properties like metabolic stability and lipophilicity. It is primarily sought by R&D and process chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group improves biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in the development and screening of new chiral catalysts.
• Fine Chemical Building Block: Utilized in custom synthesis and contract manufacturing for producing specialty fluorinated compounds.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with unique surface properties.

Basic Information

Product Name	(R)-2-((3-(Trifluoromethyl)Phenoxy)Methyl)Oxirane
CAS No.	124679-15-8
Molecular Formula	C11H11F3O2
Molecular Weight	232.20 g/mol
Synonyms	(R)-(-)-1-(3-(Trifluoromethyl)phenoxy)-2,3-epoxypropane; (R)-1-(α,α,α-Trifluoro-m-tolyloxy)-2,3-epoxypropane; (R)-3-(3-(Trifluoromethyl)phenoxy)methyl)oxirane; (R)-Glycidyl 3-(Trifluoromethyl)phenyl ether; (R)-2-[(3-Trifluoromethylphenoxy)methyl]oxirane; (R)-Epichlorohydrin 3-trifluoromethylphenyl ether derivative; (R)-TFMPO; (R)-Trifluoromethylphenyl glycidyl ether
EINECS	Contact for details

Quality Control

Every batch of (R)-2-((3-(Trifluoromethyl)Phenoxy)Methyl)Oxirane is produced under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to ensure high enantiomeric purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, chiral purity, and impurity profiles is provided with each shipment to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Refractive Index	1.470 - 1.480
Density	1.30 - 1.35 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.