Description

4-(3,4-Dichloro-Phenyl)-3,4-Dihydro-2H-Naphthalen-1-One is a high-purity organic intermediate characterized by its naphthalenone core substituted with a dichlorophenyl group. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced pesticides and herbicides, leveraging its halogenated aromatic structure.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and other functional organic materials due to its rigid, conjugated framework.
• Chemical Research: Acts as a versatile substrate for exploring new organic reactions, such as cross-coupling, hydrogenation, and cyclization methodologies.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized colorants and photostable dyes.

Basic Information

Product Name	4-(3,4-Dichloro-Phenyl)-3,4-Dihydro-2H-Naphthalen-1-One
CAS No.	124379-29-9
Molecular Formula	C₁₆H₁₂Cl₂O
Molecular Weight	291.17 g/mol
Synonyms	4-(3,4-Dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one; 4-(3,4-Dichlorophenyl)-3,4-dihydronaphthalen-1(2H)-one; 3,4-Dihydro-4-(3,4-dichlorophenyl)-2H-naphthalen-1-one; 1(2H)-Naphthalenone, 3,4-dihydro-4-(3,4-dichlorophenyl)-; 4-(3,4-Dichlorophenyl)-1-tetralone; 4-(3,4-Dichlorophenyl)-α-tetralone; 124379-29-9 (CAS)
EINECS	Contact for details

Quality Control

Our 4-(3,4-Dichloro-Phenyl)-3,4-Dihydro-2H-Naphthalen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications such as assay (HPLC), impurity profile, and physical characteristics, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.