Description

3-Methyl-5-Nitrobenzonitrile is a versatile aromatic nitrile derivative characterized by its nitro and methyl substituents. This compound serves as a critical high-purity building block in advanced organic synthesis, enabling the development of complex molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for molecules requiring a benzonitrile core with specific substitution patterns.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the nitro and nitrile functionalities are essential for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing groups.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex azo dyes and other colored compounds.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	3-Methyl-5-Nitrobenzonitrile
CAS No.	124289-22-1
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	5-Nitro-3-methylbenzonitrile; 3-Methyl-5-nitrobenzenecarbonitrile; Benzonitrile, 3-methyl-5-nitro-; 5-Cyano-1-methyl-3-nitrobenzene; 3-Methyl-5-nitro-benzonitrile; 124289-22-1; 5-Nitro-m-tolunitrile
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-Nitrobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees consistency and traceability for demanding industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.