Description

3-Bromo-5-Methylbenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and nitrile functional groups, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a precursor to various heterocycles.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitrile functionalities.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate in Suzuki, Stille, and Buchwald-Hartwig amination reactions to form new carbon-carbon and carbon-nitrogen bonds.
• Chemical Biology & Proteomics: Utilized as a molecular probe or tag in bioconjugation chemistry and target identification studies.
• Dye & Pigment Intermediate: Acts as a precursor in the synthesis of complex organic dyes and pigments for high-performance applications.

Basic Information

Product Name	3-Bromo-5-Methylbenzonitrile
CAS No.	124289-21-0
Molecular Formula	C8H6BrN
Molecular Weight	196.05 g/mol
Synonyms	5-Methyl-3-bromobenzonitrile; 3-Bromo-5-methylbenzenecarbonitrile; Benzonitrile, 3-bromo-5-methyl-; 3-Bromo-5-toluonitrile; m-Bromo-m-tolunitrile; 3-Bromo-5-cyanotoluene; 3-Bromo-5-methyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Methylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	65 - 70 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.