Description

2-(3-Bromopropyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a versatile organoboron building block, specifically a bifunctional alkyl boronic ester, that is essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates through palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific alkyl-boronate functionalities.
• Liquid Crystal & OLED Material Production: Serves as a precursor in the synthesis of advanced organic electronic materials and display components.
• Polymer & Resin Modification: Enables the functionalization of polymer chains to introduce specific bromo-alkyl or boronate ester groups for specialty materials.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugation reagents due to its reactive handles.
• Academic & Contract Research: A fundamental reagent for methodological development and complex molecule synthesis in research laboratories.

Basic Information

Product Name	2-(3-Bromopropyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	124215-44-7
Molecular Formula	C9H18BBrO2
Molecular Weight	249.0 g/mol
Synonyms	3-Bromopropylboronic Acid Pinacol Ester; 1-Bromo-3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propane; (3-Bromopropyl)boronic Acid Pinacol Ester; 2-(3-Bromopropyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl); 3-BromopropylBpin; 3-BromopropylBPin; 3-Bromopropane-1-boronic Acid Pinacol Ester; 124215-44-7
EINECS	Contact for details

Quality Control

Our 2-(3-Bromopropyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency for sensitive synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.