Description

1,3-Dioxolane, 2,2,4,5-Tetramethyl-4-(Phenylmethoxy)Methyl-, cis- is a specialized, high-purity chemical intermediate characterized by its unique cis-configuration and protected functional groups. This compound matters for its role as a critical building block in sophisticated organic synthesis, offering precise stereochemical control and reactivity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of complex molecules, such as active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block in reactions requiring high stereoselectivity, such as the construction of natural products and specialty chemicals.
• Protecting Group Chemistry: The dioxolane and benzyl-protected moiety is valuable for the temporary protection of diols or carbonyl groups during complex synthetic sequences.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced polymer precursors.
• Academic & Industrial Research: Used in methodological development and exploratory chemistry within R&D laboratories for novel compound discovery.

Basic Information

Product Name	1,3-Dioxolane, 2,2,4,5-Tetramethyl-4-(Phenylmethoxy)Methyl-, cis-
CAS No.	123920-42-3
Molecular Formula	C15H22O3
Molecular Weight	250.33 g/mol
Synonyms	cis-2,2,4,5-Tetramethyl-4-[(phenylmethoxy)methyl]-1,3-dioxolane; 4-(Benzyloxymethyl)-2,2,4,5-tetramethyl-1,3-dioxolane, cis-; (cis)-4-(Benzyloxymethyl)-2,2,4,5-tetramethyl-1,3-dioxolane; Protected Dioxolane Derivative; Benzyl-protected Tetramethyl Dioxolane; Chiral Dioxolane Acetal; (4R,5S)-4-(Benzyloxymethyl)-2,2,4,5-tetramethyl-1,3-dioxolane (stereoisomer specific)
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane, 2,2,4,5-Tetramethyl-4-(Phenylmethoxy)Methyl-, cis- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.