Description

D-Ribo-Hexonic Acid, 3-Deoxy-6-o-(1,1-Dimethylethyl)Dimethylsilyl-2-o-Methyl-4-o-(Phenylmethyl)-, .Delta.-Lactone is a sophisticated, protected sugar derivative and a key chiral building block in organic synthesis. Its value lies in its precisely defined stereochemistry and protective groups, which enable controlled reactivity for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical industry, particularly for the development of nucleoside analogs, antiviral agents, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Nucleoside & Nucleotide Chemistry: Used in the research and production of modified nucleosides with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: A valuable tool for studying glycosylation reactions and synthesizing complex oligosaccharides or glycomimetics.
• Process Development & Scale-up: Employed in optimizing synthetic routes from laboratory to pilot and commercial scale for advanced therapeutics.
• Bioconjugation & Probe Development: Useful for creating labeled sugar derivatives for biochemical and diagnostic applications.

Basic Information

Product Name	D-Ribo-Hexonic Acid, 3-Deoxy-6-o-(1,1-Dimethylethyl)Dimethylsilyl-2-o-Methyl-4-o-(Phenylmethyl)-, .Delta.-Lactone
CAS No.	123919-74-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3-Deoxy-6-O-(tert-butyldimethylsilyl)-2-O-methyl-4-O-benzyl-D-ribo-hexono-1,5-lactone; 3-Deoxy-6-O-TBDMS-2-O-methyl-4-O-benzyl-D-ribo-hexono-1,5-lactone; Protected D-ribo-Hexonolactone derivative; TBDMS-protected benzyl methyl ribonolactone
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity essential for sensitive pharmaceutical applications. Our rigorous testing includes advanced chromatographic and spectroscopic methods to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which can affect stability and reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.