Description

(R)-4,5-Isopropylidene-2-Pentanoic Acid is a high-value chiral building block and intermediate in organic synthesis. This compound matters for its role in constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise enantiomeric control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly for central nervous system (CNS) and antiviral agents.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Asymmetric Catalysis: Serves as a precursor or ligand for chiral catalysts used in stereoselective chemical transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Material Science: Potential monomer or precursor for synthesizing chiral polymers and advanced functional materials.

Basic Information

Product Name	(R)-4,5-Isopropylidene-2-Pentanoic Acid
CAS No.	123620-88-2
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(R)-4,5-O-Isopropylidene-2-pentenoic acid; (R)-4,5-Isopropylidene-2-pentenoic acid; (R)-2-Pentenoic acid, 4,5-O-(1-methylethylidene)-; (R)-4,5-O-(1-Methylethylidene)-2-pentenoic acid; (R)-4,5-Acetonide-2-pentenoic acid; (2R)-4,5-O-Isopropylidene-2-pentenoic acid; (R)-4,5-(Isopropylidenedioxy)-2-pentenoic acid
EINECS	Contact for details

Quality Control

Our (R)-4,5-Isopropylidene-2-Pentanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure compliance with high-purity standards for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.