Description

6-Fluorohexahydro-1H-1,4-Diazepine is a fluorinated heterocyclic compound belonging to the diazepine class, serving as a versatile and valuable building block in advanced organic synthesis. Its core value lies in its ability to introduce a fluorine atom and a constrained diazepine scaffold, which are critical motifs for modulating the physicochemical and biological properties of target molecules. This intermediate is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research, where the fluorinated diazepine core can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve lipophilicity and environmental persistence of active compounds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or as a structural component in organocatalysts.
• Material Science Research: Investigated as a monomer or additive for synthesizing specialty polymers with unique thermal or chemical resistance properties.
• Chemical Biology Probe: Utilized in the design of molecular probes and tags for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	6-Fluorohexahydro-1H-1,4-Diazepine
CAS No.	123187-94-0
Molecular Formula	C5H9FN2
Molecular Weight	116.14 g/mol
Synonyms	6-Fluoro-1,4-diazepane; Hexahydro-6-fluoro-1H-1,4-diazepine; 1,4-Diazepane, 6-fluoro-; 6-Fluoroperhydro-1H-1,4-diazepine; 6-Fluorohexahydro-1H-1,4-diazepine; Fluorinated Diazepine Intermediate; 6-Fluoro-1,4-diazacycloheptane
EINECS	Contact for details

Quality Control

Our 6-Fluorohexahydro-1H-1,4-Diazepine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.