Description

tert-Butyl 2-(2-Bromophenyl)Acetate is a high-purity organic building block and ester derivative, essential for advanced synthetic chemistry. This compound serves as a critical intermediate in the development of complex molecules, offering a protected carboxylic acid group and a versatile bromoarene handle for cross-coupling reactions. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for constructing active pharmaceutical ingredients (APIs), ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a substituted phenylacetic acid scaffold.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: The bromophenyl moiety acts as an excellent substrate for Suzuki, Heck, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for exploring new chemical entities in discovery chemistry.
• Chemical Library Building: Employed in combinatorial chemistry and high-throughput screening for generating diverse compound libraries.

Basic Information

Product Name	tert-Butyl 2-(2-Bromophenyl)Acetate
CAS No.	123088-07-3
Molecular Formula	C₁₂H₁₅BrO₂
Molecular Weight	271.15 g/mol
Synonyms	2-(2-Bromophenyl)acetic acid tert-butyl ester; tert-Butyl (2-bromophenyl)acetate; 2-Bromobenzeneacetic acid 1,1-dimethylethyl ester; (2-Bromophenyl)acetic acid tert-butyl ester; 1,1-Dimethylethyl 2-(2-bromophenyl)acetate; 2-(2-Bromophenyl)acetic acid 1,1-dimethylethyl ester; tert-Butyl 2-(o-bromophenyl)acetate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(2-Bromophenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.