Description

4,5-Hexadienoic Acid, 2-Amino-3-Methyl-, Methyl Ester is a specialized chiral building block featuring both an amino acid ester and a conjugated diene functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel APIs, especially those requiring amino acid-derived scaffolds.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with specific stereochemistry.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and conformationally constrained molecules.
• Organic Synthesis Reagent: Serves as a versatile precursor for Diels-Alder reactions and other cycloadditions to construct complex ring systems.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and flavors/fragrances.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	4,5-Hexadienoic Acid, 2-Amino-3-Methyl-, Methyl Ester
CAS No.	122885-34-1
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Methyl 2-amino-3-methyl-4,5-hexadienoate; 2-Amino-3-methyl-4,5-hexadienoic acid methyl ester; 4,5-Hexadienoic acid, 2-amino-3-methyl-, methyl ester; 2-Amino-3-methylhexa-4,5-dienoic acid methyl ester; Methyl (2E)-2-amino-3-methylhexa-4,5-dienoate; Allenic amino acid ester; 3-Methyl-2-aminopenta-3,4-dienoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 4,5-Hexadienoic Acid, 2-Amino-3-Methyl-, Methyl Ester is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.