Description

(3Z,5E,8R,9E,11Z,14S,16S,17E,19E,24R)-8,14,16-Trihydroxy-24-Methyl-1-Oxacyclotetracosa-3,5,9,11,17,19-Hexaen-2-One is a complex macrolide compound with a specific stereochemical configuration. This molecule is of significant interest in advanced pharmaceutical research and development due to its intricate polyene and polyol structure, which is often associated with potent biological activity. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, pharmacology, and process development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents, particularly in the development of antifungal, antibiotic, or anticancer compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related active pharmaceutical ingredients (APIs) and finished drug products.
• Medicinal Chemistry Research: A valuable tool for structure-activity relationship (SAR) studies to optimize biological potency and pharmacokinetic properties.
• Biochemical Research: Employed in studies investigating molecular mechanisms of action, enzyme inhibition, or cellular signaling pathways.
• Process Chemistry Development: Used as a benchmark in scaling up synthetic routes and optimizing manufacturing processes for complex macrolides.

Basic Information

Product Name	(3Z,5E,8R,9E,11Z,14S,16S,17E,19E,24R)-8,14,16-Trihydroxy-24-Methyl-1-Oxacyclotetracosa-3,5,9,11,17,19-Hexaen-2-One
CAS No.	122540-27-6
Molecular Formula	C25H38O6
Molecular Weight	434.57 g/mol
Synonyms	24-Methyl-8,14,16-trihydroxy-1-oxacyclotetracosa-3,5,9,11,17,19-hexaen-2-one; (3Z,5E,9E,11Z,17E,19E)-8,14,16-Trihydroxy-24-methyl-1-oxacyclotetracosa-3,5,9,11,17,19-hexaen-2-one; Macrolide derivative 122540-27-6; Polyene macrolide intermediate; 1-Oxacyclotetracosa-3,5,9,11,17,19-hexaen-2-one, 8,14,16-trihydroxy-24-methyl-, (3Z,5E,8R,9E,11Z,14S,16S,17E,19E,24R)-
EINECS	Contact for details

Quality Control

Our (3Z,5E,8R,9E,11Z,14S,16S,17E,19E,24R)-8,14,16-Trihydroxy-24-Methyl-1-Oxacyclotetracosa-3,5,9,11,17,19-Hexaen-2-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.