Description

3-Amino-2-(Trifluoromethyl)Propionic Acid is a high-value, non-natural amino acid derivative characterized by its trifluoromethyl group, which imparts unique physicochemical properties. This compound is a critical building block in modern organic synthesis, offering enhanced metabolic stability and lipophilicity to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of protease inhibitors, enzyme modulators, and other bioactive molecules where the trifluoromethyl group is crucial for activity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its stability to improve product efficacy and environmental profile.
• Peptide Mimetics & Drug Design: Serves as a non-proteinogenic amino acid analog in peptide-based drug discovery to enhance binding affinity, selectivity, and in vivo stability.
• Material Science Research: Employed in the synthesis of specialized polymers, ligands, and fluorinated compounds for advanced material applications.
• Chemical Biology Probes: Utilized as a building block for creating labeled compounds and molecular probes used in mechanistic studies and diagnostic research.

Basic Information

Product Name	3-Amino-2-(Trifluoromethyl)Propionic Acid
CAS No.	122490-10-2
Molecular Formula	C4H6F3NO2
Molecular Weight	157.09 g/mol
Synonyms	2-(Trifluoromethyl)-3-aminopropanoic Acid; β-Amino-β-trifluoromethylpropionic Acid; 3-Amino-2-trifluoromethylpropanoic Acid; (R/S)-3-Amino-2-(trifluoromethyl)propionic Acid; DL-3-Amino-2-(trifluoromethyl)propionic Acid; 2-Trifluoromethyl-β-alanine; Amino(trifluoromethyl)propionic Acid
EINECS	Contact for details

Quality Control

Our 3-Amino-2-(Trifluoromethyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.