Description

3-Deoxy-C(3)-Fluoromethyleneglucose is a fluorinated carbohydrate derivative, a valuable synthetic intermediate in medicinal chemistry and biochemical research. Its unique structure, featuring a fluoromethylene group at the C-3 position, makes it a crucial building block for developing novel enzyme inhibitors and molecular probes. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery programs targeting metabolic pathways and glycosidase enzymes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel glycosidase inhibitors for potential therapeutic applications.
• Biochemical Research: Used as a stable, fluorine-labeled analog of glucose to study carbohydrate metabolism and enzyme mechanisms.
• Probe Development: Serves as a building block for Positron Emission Tomography (PET) tracer candidates targeting glucose transporters (GLUT).
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Glycobiology Studies: A tool compound for investigating glycan processing and the role of specific glycosyl hydrolases.

Basic Information

Product Name	3-Deoxy-C(3)-Fluoromethyleneglucose
CAS No.	122378-47-6
Molecular Formula	C7H11FO5
Molecular Weight	194.16 g/mol
Synonyms	3-Deoxy-3-fluoromethyleneglucose; 3-Deoxy-3-(fluoromethylene)-D-glucose; 3-Fluoromethyleneglucose; 1,5-Anhydro-2,4,6-tri-O-benzyl-3-deoxy-3-fluoromethylene-D-glucitol (protected form precursor); Fluorinated glucose analog; 3-Fluoroalkylidene glucose
EINECS	Contact for details

Quality Control

Our 3-Deoxy-C(3)-Fluoromethyleneglucose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR (¹H, ¹³C, ¹⁹F) for structural confirmation, to ensure consistency and reliability for research applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be sealed under an inert atmosphere after opening and desiccated for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.