Description

1-(3-Bromo-4-Methoxyphenyl)-2,2,2-Trifluoroethanone is a high-purity trifluoromethyl ketone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and methoxy substituents on the aromatic ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl or aryl bromide functional groups.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis and organocatalysts.
• Fluorine Chemistry Studies: An important compound for academic and industrial research exploring the properties and reactivity of fluorinated aromatic ketones.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	1-(3-Bromo-4-Methoxyphenyl)-2,2,2-Trifluoroethanone
CAS No.	122243-36-1
Molecular Formula	C9H6BrF3O2
Molecular Weight	283.04 g/mol
Synonyms	3'-Bromo-4'-methoxy-2,2,2-trifluoroacetophenone; 2,2,2-Trifluoro-1-(3-bromo-4-methoxyphenyl)ethanone; 1-(3-Bromo-4-methoxyphenyl)-2,2,2-trifluoroethan-1-one; 3-Bromo-4-methoxy-α,α,α-trifluoroacetophenone; α,α,α-Trifluoro-3-bromo-4-methoxyacetophenone; (3-Bromo-4-methoxyphenyl)trifluoromethyl ketone; TFAP-Br-OMe derivative
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-4-Methoxyphenyl)-2,2,2-Trifluoroethanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and GC-MS. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.