Description

Ethanone, 2,2,2-Trifluoro-1-[4-(Methylthio)Phenyl]- (9Ci) is a high-purity trifluoromethyl ketone derivative characterized by its unique phenylthioether substituent. This compound serves as a versatile and valuable building block and intermediate in advanced organic synthesis, particularly where the introduction of a trifluoroacetyl group is required. It is primarily utilized by research institutions and industrial R&D departments engaged in the development of pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing trifluoromethyl motifs which enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group is a critical functional moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Intermediate in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-[4-(Methylthio)Phenyl]- (9Ci)
CAS No.	122243-33-8
Molecular Formula	C9H7F3OS
Molecular Weight	220.21 g/mol
Synonyms	2,2,2-Trifluoro-1-[4-(methylthio)phenyl]ethanone; 4'-(Methylthio)-2,2,2-trifluoroacetophenone; 1-[4-(Methylsulfanyl)phenyl]-2,2,2-trifluoroethanone; 4-(Methylthio)phenyl trifluoromethyl ketone; α,α,α-Trifluoro-4'-(methylthio)acetophenone; p-(Methylthio)phenyl trifluoromethyl ketone; TFMPK derivative
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-[4-(Methylthio)Phenyl]- (9Ci) is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.