Description

Gymnemic Acid I CAS NO 122168-40-5 is a specific, high-purity triterpenoid saponin isolated from the leaves of the *Gymnema sylvestre* plant. This compound is of significant commercial and research interest due to its potent and selective activity as a natural sweetness suppressor, blocking the perception of sweet tastes on the tongue. It is a critical raw material for manufacturers in the nutraceutical, dietary supplement, and functional food industries, as well as for research institutions focused on taste physiology, diabetes, and obesity management.

Application

• Primary active ingredient in dietary supplements and weight management formulations targeting sugar cravings.
• Key component in functional foods and beverages designed for glycemic control and reduced-calorie profiles.
• Standard reference material for analytical testing and quality control of *Gymnema sylvestre* extracts and finished products.
• Essential biochemical tool in pharmacological and physiological research studying sweet taste receptors (T1R2/T1R3).
• Used in cosmeceutical applications exploring anti-inflammatory and skin-beneficial properties of triterpenoids.
• Starting material for the semi-synthesis of novel derivatives with enhanced bioactivity or modified properties.

Basic Information

Product Name	Gymnemic Acid I
CAS No.	122168-40-5
Molecular Formula	C₄₃H₆₈O₁₄
Molecular Weight	809.0 g/mol
Synonyms	Gymnemic Acid I; Gymnemic Acid A1; Gymnemic Acid III (historical); (3β,4α,16β,21β,22α)-21,22-Bis[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-16-(2-methyl-1-oxobutoxy)olean-12-en-3,4,28,29-tetrol 3,29-bis(6-deoxy-α-L-mannopyranoside); Gymnema Saponin; Gymnemic Acid (principal component)
EINECS	Contact for details

Quality Control

Our Gymnemic Acid I is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding nutraceutical and research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by HPLC, MS, and NMR. We support compliance with cGMP, ISO, and relevant food safety standards for ingredient suppliers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥95.0% (Anhydrous basis)
Loss on Drying	≤5.0%
Residue on Ignition	≤1.0%
Heavy Metals (as Pb)	≤20 ppm
Solvent Residues	Meets ICH guidelines
Microbiological Analysis	Meets standard limits for dietary ingredients

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.