Description

(+/-)-α-Bromo-α-Methyl-γ-Butyrolactone CAS NO 122040-92-0 is a versatile brominated lactone derivative that serves as a critical chiral building block and alkylating agent in advanced organic synthesis. Its unique structure, featuring both a reactive bromine atom and a lactone ring, makes it invaluable for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other high-value intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drug candidates, particularly those requiring γ-lactone or α-branched carboxylic acid motifs.
• Agrochemical Synthesis: Used as an alkylating agent to introduce the α-methyl-γ-butyrolactone moiety into novel herbicide and fungicide molecules.
• Asymmetric Synthesis: Serves as a substrate for kinetic resolutions or chiral pool synthesis to access enantiomerically enriched compounds.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for specialty polymers with tailored degradation profiles.
• Material Science Research: Employed in the development of novel organic materials and liquid crystals.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and new reaction development.

Basic Information

Product Name	(+/-)-α-Bromo-α-Methyl-γ-Butyrolactone
CAS No.	122040-92-0
Molecular Formula	C6H7BrO2
Molecular Weight	191.02 g/mol
Synonyms	α-Bromo-α-methyl-γ-butyrolactone; 3-Bromo-3-methyl-dihydrofuran-2(3H)-one; 2(3H)-Furanone, 3-bromo-3-methyl-dihydro-; 3-Bromo-3-methylbutyrolactone; (±)-α-Bromo-α-methyl-γ-butyrolactone; Bromomethylbutyrolactone; α-Bromo-α-methyl-γ-butyrolactone
EINECS	Contact for details

Quality Control

Our (+/-)-α-Bromo-α-Methyl-γ-Butyrolactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. For cGMP or other specific regulatory grade requirements, please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.