Description

1,3-Dioxane-4-Carboxaldehyde, 2,2-Dimethyl-, (S)- (9Ci) is a high-purity chiral aldehyde derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined, protected aldehyde functionality essential for constructing complex molecular architectures. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries for the production of active pharmaceutical ingredients (APIs) and specialty intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Used in stereoselective reactions, including aldol condensations and nucleophilic additions, to introduce chiral centers with high enantiomeric purity.
• Natural Product Synthesis: Serves as a precursor in the total synthesis of natural products and complex bioactive compounds requiring specific stereochemistry.
• Ligand and Catalyst Development: Employed in the research and development of novel chiral ligands and organocatalysts for catalytic asymmetric transformations.
• Fine Chemical Production: Utilized in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic and Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in both academic laboratories and industrial R&D facilities.

Basic Information

Product Name	1,3-Dioxane-4-Carboxaldehyde, 2,2-Dimethyl-, (S)- (9Ci)
CAS No.	121935-06-6
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(S)-2,2-Dimethyl-1,3-dioxane-4-carboxaldehyde; (4S)-2,2-Dimethyl-1,3-dioxane-4-carbaldehyde; (S)-4-Formyl-2,2-dimethyl-1,3-dioxane; L-Glyceraldehyde Acetonide; (S)-Glyceraldehyde Acetonide; (S)-1,2-O-Isopropylidene glyceraldehyde; (S)-2,2-Dimethyl-1,3-dioxolane-4-carboxaldehyde (related structure)
EINECS	Contact for details

Quality Control

Our 1,3-Dioxane-4-Carboxaldehyde, 2,2-Dimethyl-, (S)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain purity and prevent degradation. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.