Description

2-Furancarboxylicacid,3-Fluorotetrahydro-5-Methyl-,[2R-(2Alpha,3Beta,5Alpha)]-(9Ci) is a high-purity, stereochemically defined fluorinated furan derivative of significant interest in advanced synthetic chemistry. This compound serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the fluorinated furan moiety can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex fluorinated organic compounds for material science and electronic chemical applications.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including novel fluorination and cyclization reactions.

Basic Information

Product Name	2-Furancarboxylicacid,3-Fluorotetrahydro-5-Methyl-,[2R-(2Alpha,3Beta,5Alpha)]-(9Ci)
CAS No.	121911-25-9
Molecular Formula	C7H9FO3
Molecular Weight	160.14 g/mol
Synonyms	(2R,3S,5R)-3-Fluoro-5-methyltetrahydrofuran-2-carboxylic acid; 3-Fluoro-5-methyltetrahydro-2-furancarboxylic acid, (2R,3S,5R)-; Tetrahydro-3-fluoro-5-methyl-2-furancarboxylic acid, (2R,3S,5R)-; (2R,3S,5R)-3-Fluoro-5-methyloxolane-2-carboxylic acid; Fluorinated tetrahydrofuran carboxylic acid derivative; Chiral fluorofuran carboxylate; 121911-25-9
EINECS	Contact for details

Quality Control

We supply this high-value intermediate under strict quality protocols, with standard purity grades meeting or exceeding 97% (by HPLC). Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing chiral purity (enantiomeric excess), assay, and impurity profiles. Our quality system ensures traceability and consistency, supporting cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.