Description

2'-Chloro-4',5'-Difluoroacetophenone is a high-purity fluorinated acetophenone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique halogenated aromatic structure, which enables precise molecular modifications essential for developing complex, high-performance compounds. This product is primarily needed by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors, where it is utilized to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring fluorinated and chlorinated aromatic motifs for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its difluoro and chloro substituents contribute to product efficacy and environmental profile.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, where its specific halogen pattern can influence material properties.
• Organic Synthesis Reagent: Functions as a versatile precursor for further chemical transformations, including nucleophilic substitution and carbonyl chemistry, in custom synthesis projects.

Basic Information

Product Name	2'-Chloro-4',5'-Difluoroacetophenone
CAS No.	121872-94-4
Molecular Formula	C8H5ClF2O
Molecular Weight	190.57 g/mol
Synonyms	1-(2-Chloro-4,5-difluorophenyl)ethanone; 2-Chloro-4,5-difluoroacetophenone; 2-Chloro-4,5-difluoro-1-acetylbenzene; 2-Chloro-4,5-difluorophenyl methyl ketone; Acetophenone, 2'-chloro-4',5'-difluoro-; Ethanone, 1-(2-chloro-4,5-difluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Chloro-4',5'-Difluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent contamination and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.