Description

Norleucine,6-Cyano-(9Ci) is a specialized non-proteinogenic amino acid derivative featuring a cyano functional group. This compound serves as a valuable high-purity building block and key synthetic intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for peptide mimetics and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that incorporate modified amino acid structures.
• Peptidomimetics & Drug Discovery: The cyano-norleucine moiety is employed to introduce specific steric, electronic, or metabolic stability properties into peptide-based drug candidates.
• Chemical Biology Probes: Serves as a building block for creating labeled or tagged amino acid analogs used in mechanistic studies and proteomics.
• Fine Chemical Synthesis: Acts as a chiral synthon for the asymmetric synthesis of complex natural products and specialty chemicals.
• Material Science: Potential monomer or modifier in the research of functional polymers and advanced materials.

Basic Information

Product Name	Norleucine,6-Cyano-(9Ci)
CAS No.	121703-83-1
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	6-Cyano-2-aminohexanoic acid; 2-Amino-6-cyanohexanoic acid; 6-Cyano-L-norleucine; (S)-2-Amino-6-cyanohexanoic acid; Norleucine, 6-cyano-; 6-Cyanonorleucine; L-6-Cyanonorleucine; 2-Amino-6-cyanocaproic acid
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.