Description

tert-Butyl 4-(Chloromethyl)Benzoate is a versatile and high-purity organic building block, specifically a benzoate ester derivative with a reactive chloromethyl group. This compound is valued for its role as a key synthetic intermediate in the production of complex molecules, offering a protected carboxylic acid functionality and a site for further functionalization. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators, where its structure serves as a core scaffold.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing advanced organic electronic materials used in displays and lighting.
• Polymer & Resin Modifier: Employed to introduce benzoate and reactive chloromethyl groups into polymer chains, modifying properties like solubility, adhesion, and thermal stability.
• Organic Synthesis & Research Chemical: A valuable reagent in academic and industrial R&D labs for constructing complex organic molecules, including natural product analogs and molecular probes.
• Peptide & Protein Conjugation: The chloromethyl group can be utilized for linking this moiety to peptides or proteins, useful in bioconjugation and prodrug strategies.

Basic Information

Product Name	tert-Butyl 4-(Chloromethyl)Benzoate
CAS No.	121579-86-0
Molecular Formula	C12H15ClO2
Molecular Weight	226.70 g/mol
Synonyms	4-(Chloromethyl)benzoic acid tert-butyl ester; tert-Butyl p-(chloromethyl)benzoate; Benzoic acid, 4-(chloromethyl)-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-(chloromethyl)benzoate; p-(Chloromethyl)benzoic acid tert-butyl ester; 4-(tert-Butoxycarbonyl)benzyl chloride; TBBC
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Chloromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.