Description

5-Benzyl-3-Bromo-1,2,4-Oxadiazole is a high-value, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a reactive bromine substituent and a versatile benzyl-protected oxadiazole scaffold, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key precursor for novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used to construct advanced herbicide and fungicide molecules, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a building block for functional polymers and liquid crystals, where the oxadiazole unit contributes to electronic properties.
• Chemical Biology Probe Development: Employed in creating tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Heterocyclic Library Synthesis: A versatile starting material for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	5-Benzyl-3-Bromo-1,2,4-Oxadiazole
CAS No.	121562-10-5
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	3-Bromo-5-benzyl-1,2,4-oxadiazole; 5-Benzyl-3-bromo-1,2,4-oxadiazole; 1,2,4-Oxadiazole, 3-bromo-5-(phenylmethyl)-; Benzyl 3-bromo-1,2,4-oxadiazole; 3-Bromo-5-(phenylmethyl)-1,2,4-oxadiazole; 3-Bromo-5-benzyl-[1,2,4]oxadiazole
EINECS	Contact for details

Quality Control

Our 5-Benzyl-3-Bromo-1,2,4-Oxadiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.