Description

2-Thiophenecarboxamide, n-(6-Amino-1,2,3,4-Tetrahydro-2,4-Dioxo-1,3-Dipropyl-5-Pyrimidinyl)- is a high-purity, specialized heterocyclic compound featuring a fused pyrimidine and thiophene structure. This molecule serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of proprietary drug candidates, particularly those targeting enzyme inhibition.
• Biochemical Research: Used as a reference standard or precursor in life science research to study biological pathways and mechanisms.
• Organic Synthesis: Serves as a versatile scaffold for medicinal chemists to develop new chemical entities with potential therapeutic value.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional laboratories for exploratory chemistry and the development of novel synthetic methodologies.

Basic Information

Product Name	2-Thiophenecarboxamide, n-(6-Amino-1,2,3,4-Tetrahydro-2,4-Dioxo-1,3-Dipropyl-5-Pyrimidinyl)-
CAS No.	121543-19-9
Molecular Formula	C15H20N4O3S
Molecular Weight	336.41 g/mol
Synonyms	N-(6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)-2-thiophenecarboxamide; 1,3-Dipropyl-6-amino-5-(2-thiophenecarboxamido)uracil; 5-(2-Thiophenecarboxamido)-1,3-dipropyl-6-aminouracil; 6-Amino-1,3-dipropyl-5-(2-thiophenecarboxamido)-1,2,3,4-tetrahydro-2,4-pyrimidinedione; A-80226; A 80226; A80226
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with client specifications. We support development and commercial projects requiring material produced under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.