Description

7-Oxabicyclo[4.1.0]Heptane, 4-Ethynyl-1-Methyl-, [1S-(1Alpha,4Beta,6Alpha)]- (9Ci) is a high-purity, stereochemically defined oxirane-fused bicyclic compound featuring a reactive ethynyl group. This unique molecular architecture makes it a versatile and valuable chiral building block for advanced organic synthesis, particularly in the development of complex pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce constrained, three-dimensional complexity into drug candidates.
• Asymmetric Synthesis: Employed as a precursor or reagent in catalytic asymmetric reactions to construct stereogenic centers with high enantiomeric purity.
• Agrochemical Synthesis: Potential application in the development of novel, high-performance crop protection agents with specific modes of action.
• Material Science Research: Investigated as a monomer or cross-linking agent for the synthesis of specialized polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms or protein-ligand interactions via its reactive alkyne handle.

Basic Information

Product Name	7-Oxabicyclo[4.1.0]Heptane, 4-Ethynyl-1-Methyl-, [1S-(1Alpha,4Beta,6Alpha)]- (9Ci)
CAS No.	121383-74-2
Molecular Formula	C8H10O
Molecular Weight	122.16 g/mol
Synonyms	4-Ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane, (1S,4R,6R)-4-Ethynyl-1-methyl-7-oxabicyclo[4.1.0]heptane; 1-Methyl-4-ethynyl-7-oxabicyclo[4.1.0]heptane; (1S,4R,6R)-1-Methyl-4-ethynyl-7-oxabicyclo[4.1.0]heptane; Chiral Oxirane Fused Cycloheptane Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques (GC, HPLC, NMR) to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing specific batch results are available upon request. Our quality management system adheres to cGMP principles for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.