Description

Ethyl 3-Methylamino-4,4,4-Trifluorocrotonate is a specialized fluorinated organic compound that serves as a valuable building block in advanced chemical synthesis. Its molecular structure, featuring a trifluoromethyl group and an enamine ester moiety, makes it a key intermediate for introducing fluorinated motifs into target molecules. This compound is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated heterocycles or complex amine structures.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Fluorinated Building Block: Employed in organic and medicinal chemistry for the construction of complex molecules, leveraging its reactivity for C-C and C-N bond-forming reactions.
• Material Science Research: Acts as a monomer or modifier in the development of specialty polymers and advanced materials with unique surface properties.
• Chemical Research & Development: Serves as a versatile reagent for method development and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Product Name	Ethyl 3-Methylamino-4,4,4-Trifluorocrotonate
CAS No.	121303-76-2
Molecular Formula	C7H10F3NO2
Molecular Weight	197.16 g/mol
Synonyms	Ethyl (Z)-3-(Methylamino)-4,4,4-trifluorobut-2-enoate; 4,4,4-Trifluoro-3-(methylamino)-2-butenoic Acid Ethyl Ester; 3-Methylamino-4,4,4-trifluorocrotonic Acid Ethyl Ester; Ethyl 3-(Methylamino)-4,4,4-trifluorocrotonate; (Z)-Ethyl 3-(methylamino)-4,4,4-trifluorobut-2-enoate; Ethyl β-Methylamino-α-(trifluoromethyl)acrylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request. Our quality management system supports the needs of cGMP and ISO-certified manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.