Description

n-[4-(1,1-Dimethylethyl)Phenyl]-1,1,1-Trifluoro-n-[(Trifluoromethyl)Sulfonyl]-Methanesulfonamide is a specialized organofluorine sulfonamide compound, valued for its unique chemical structure that imparts high stability and reactivity. This compound serves as a critical intermediate or reagent in advanced synthetic chemistry, particularly where the introduction of trifluoromethanesulfonyl (triflyl) and related fluorinated groups is required. It is essential for research and development in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those requiring fluorinated sulfonamide moieties for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Advanced Material Research: Serves as a precursor or functionalizing agent in the development of specialty polymers, coatings, and electronic materials that benefit from fluorinated components.
• Organic Synthesis Reagent: Acts as a versatile reagent in academic and industrial laboratories for introducing the N-(triflyl) group, facilitating various C-N and C-S bond-forming reactions.
• Catalyst Ligand Precursor: Potential use in the design and synthesis of novel ligands for metal catalysis, leveraging the electron-withdrawing nature of the sulfonyl groups.
• Chemical Biology Probes: Employed in the creation of chemical probes for studying enzyme mechanisms and protein interactions where a specific, stable label is needed.

Basic Information

Item	Details
Product Name	n-[4-(1,1-Dimethylethyl)Phenyl]-1,1,1-Trifluoro-n-[(Trifluoromethyl)Sulfonyl]-Methanesulfonamide
CAS No.	121287-02-3
Molecular Formula	C13H15F6NO4S2
Molecular Weight	427.38 g/mol
Synonyms	N-(4-tert-Butylphenyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide; 1,1,1-Trifluoro-N-[(trifluoromethyl)sulfonyl]-N-[4-(1,1-dimethylethyl)phenyl]methanesulfonamide; N-(4-tert-Butylphenyl)triflimide; N-(4-tert-Butylphenyl)bis(trifluoromethanesulfonyl)imide; 4-tert-Butylphenyl TFSI Amide; tert-Butylphenyl Triflimide; N-(p-tert-Butylphenyl)trifluoromethanesulfonimide
EINECS	Contact for details

Quality Control

Our n-[4-(1,1-Dimethylethyl)Phenyl]-1,1,1-Trifluoro-n-[(Trifluoromethyl)Sulfonyl]-Methanesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.