Description

4-(n-Methylaminocarbonyl)Phenylboronic Acid is a high-purity boronic acid derivative featuring a carboxamide functional group. This compound is a critical building block in modern synthetic chemistry, particularly valued for its role in Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: A versatile organoboron reagent for forming carbon-carbon bonds to construct complex biaryl structures common in drug discovery.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Building block for creating organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors for diagnostic applications.
• Process Chemistry & Scale-up: Serves as a reliable intermediate for process optimization and pilot-scale manufacturing in fine chemical production.

Basic Information

Product Name	4-(n-Methylaminocarbonyl)Phenylboronic Acid
CAS No.	121177-82-0
Molecular Formula	C9H12BNO3
Molecular Weight	192.01 g/mol
Synonyms	4-(Methylcarbamoyl)phenylboronic acid; [4-(Methylaminocarbonyl)phenyl]boronic acid; N-Methyl-4-boronobenzamide; p-(N-Methylcarbamoyl)phenylboronic acid; B-[4-(Methylaminocarbonyl)phenyl]boronic acid; 4-Carbamoylphenylboronic acid N-methyl derivative; 4-Boronobenzoic acid methylamide
EINECS	Contact for details

Quality Control

Our 4-(n-Methylaminocarbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.