Description

(R)-(+)-1 1 1-Trifluorooctan-2-Ol 97 is a high-purity, chiral fluorinated alcohol building block, essential for introducing the trifluoromethyl group and stereochemical control into advanced molecular architectures. Its value lies in enabling the synthesis of complex, optically active compounds with enhanced metabolic stability and lipophilicity, which are critical for modern pharmaceutical and agrochemical discovery. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, chiral ligand synthesis, and specialty polymer modification.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used to construct chiral, fluorinated analogs of pesticides and herbicides to improve efficacy and environmental profile.
• Chiral Ligand & Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Monomers: Incorporated into specialty polymers and liquid crystals to modify surface properties, refractive index, and chemical resistance.
• Fluorine-19 NMR Spectroscopy: Can be utilized as a standard or probe molecule in analytical chemistry due to its distinct fluorine signature.
• Chemical Biology Probes: Acts as a building block for creating fluorinated probes to study biological processes and protein interactions.

Basic Information

Product Name	(R)-(+)-1 1 1-Trifluorooctan-2-Ol 97
CAS No.	121170-45-4
Molecular Formula	C8H15F3O
Molecular Weight	184.20 g/mol
Synonyms	(R)-1,1,1-Trifluoro-2-octanol; (R)-(+)-1,1,1-Trifluoro-2-octanol; (R)-1,1,1-Trifluoro-octan-2-ol; (R)-2-Octanol, 1,1,1-trifluoro-; (R)-α-(Trifluoromethyl)heptyl alcohol; (R)-Trifluoromethyl heptyl carbinol; (R)-TFOH; (R)-TFO
EINECS	Contact for details

Quality Control

Our (R)-(+)-1 1 1-Trifluorooctan-2-Ol 97 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the specified 97% minimum purity and enantiomeric excess (e.e.) requirements. Certificates of Analysis (COA) with detailed chromatographic data (GC/HPLC) are provided to guarantee traceability, consistency, and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.