Description

2-(2-(Ethylthiomethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity organoboron reagent featuring a unique phenyl ring substituted with an ethylthiomethyl group. This compound is a critical building block in modern synthetic chemistry, enabling the formation of carbon-carbon and carbon-heteroatom bonds via Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or heteroaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the incorporation of specific sulfur and boron-containing functional groups.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	2-(2-(Ethylthiomethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	121114-64-5
Molecular Formula	C15H23BO2S
Molecular Weight	278.22 g/mol
Synonyms	[2-(Ethylthiomethyl)phenyl]boronic acid pinacol ester; 2-(2-(Ethylthiomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-((Ethylthio)methyl)phenyl)boronic acid pinacol ester; Pinacol [2-(ethylthiomethyl)phenyl]boronate; 2-(Ethylthiomethyl)benzeneboronic acid pinacol ester; B-[2-[(Ethylthio)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 121114-64-5
EINECS	Contact for details

Quality Control

Our production of 2-(2-(Ethylthiomethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.