Description

Benzylboronic Acid Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it ideal for handling, storage, and use in demanding synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a monomer or building block for creating advanced organic electronic materials and polymers.
• Chemical Research & Development: A versatile synthon for constructing complex molecular architectures in academic and industrial R&D labs.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Process Chemistry: Valued for its stability in large-scale manufacturing processes requiring robust and reliable boronic acid equivalents.

Basic Information

Product Name	Benzylboronic Acid Pinacol Ester
CAS No.	121074-61-1
Molecular Formula	C13H19BO2
Molecular Weight	218.10 g/mol
Synonyms	Benzylboronic Acid Pinacol Ester; (Benzylboronic Acid) Pinacol Ester; Benzylboronic Acid, Pinacol Ester; Benzylboronic Acid Pinanediol Ester (common alternative); Benzyl-B(pin); Pinacol Benzylboronate; 2-(Phenylmethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzyl MIDA Boronate (related protected form).
EINECS	Contact for details

Quality Control

Our Benzylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening a new container to prevent hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.