Description

2-Phenylacetylene-1-Boronic Acid Diisopropyl Ester is a versatile organoboron building block, specifically a protected boronic ester derivative. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and conjugated systems in advanced chemical synthesis. This compound is essential for researchers and process chemists in pharmaceutical development, agrochemical research, and materials science, particularly in the synthesis of liquid crystals and organic electronic materials.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex aromatic and heteroaromatic scaffolds in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific biphenyl or styryl structures.
• Materials Science: Serves as a monomer or building block for creating conjugated polymers and organic semiconductors for OLEDs and photovoltaic applications.
• Liquid Crystal Manufacturing: Employed in the synthesis of advanced liquid crystal molecules for display technologies.
• Chemical Biology & Probe Development: Utilized in the creation of bioconjugates and molecular probes for diagnostic and research purposes.
• Academic & Process R&D: A fundamental tool for methodology development and scaling novel carbon-carbon bond-forming reactions in laboratory and pilot plant settings.

Basic Information

Product Name	2-Phenylacetylene-1-Boronic Acid Diisopropyl Ester
CAS No.	121021-26-9
Molecular Formula	C14H19BO2
Molecular Weight	230.11 g/mol
Synonyms	Diisopropyl (2-Phenylethynyl)boronate; (2-Phenylethynyl)boronic Acid Diisopropyl Ester; 2-Phenylethynylboronic Acid Diisopropyl Ester; Diisopropoxy(2-phenylethynyl)borane; B-(2-Phenylethynyl)boronic Acid Diisopropyl Ester; Phenylacetylene Boronic Acid Diisopropyl Ester; (Phenylethynyl)diisopropoxyborane
EINECS	Contact for details

Quality Control

Our 2-Phenylacetylene-1-Boronic Acid Diisopropyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.