Description

4-Hydroxy-4-(Trifluoromethyl)Cyclohexan-1-One is a versatile fluorinated organic building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a trifluoromethyl group and a ketone functionality on a cyclohexane ring, makes it a valuable precursor for creating complex molecules with enhanced properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly those requiring the metabolic stability and lipophilicity imparted by the trifluoromethyl group.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced materials with specific thermal or chemical resistance profiles.
• Liquid Crystal & OLED Materials: Investigated as a building block for fluorinated components in electronic display and lighting technologies.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex, fluorinated cyclic compounds and exploring new catalytic transformations.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing novel aromatic compounds with unique organoleptic properties.

Basic Information

Product Name	4-Hydroxy-4-(Trifluoromethyl)Cyclohexan-1-One
CAS No.	120929-90-0
Molecular Formula	C7H9F3O2
Molecular Weight	182.14 g/mol
Synonyms	4-(Trifluoromethyl)-4-hydroxycyclohexanone; 4-Hydroxy-4-(trifluoromethyl)cyclohexanone; 4-Hydroxy-α,α,α-trifluoromethylcyclohexanemethanol; 1-Cyclohexanone, 4-hydroxy-4-(trifluoromethyl)-; 4-Hydroxy-4-trifluoromethylcyclohexanone; 4-(Trifluoromethyl)-1,4-cyclohexanediol mono ketone
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-4-(Trifluoromethyl)Cyclohexan-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP and ISO compliant production for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.