Description

4-((tert-Butyldimethylsilyl)Oxy)Benzaldehyde is a high-value, protected benzaldehyde derivative featuring a tert-butyldimethylsilyl (TBDMS) ether group. This compound is a crucial advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, prized for its role in introducing the protected hydroxybenzaldehyde moiety into complex molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active compounds and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring protected phenolic aldehyde functionalities.
• Organic Synthesis Reagent: Used in multi-step synthesis for the preparation of ligands, catalysts, and advanced materials.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Precursor for synthesizing monomers or functional units for specialty polymers and liquid crystals.
• Academic & Industrial R&D: Serves as a standard or starting material in research laboratories for methodological development and discovery chemistry.

Basic Information

Product Name	4-((tert-Butyldimethylsilyl)Oxy)Benzaldehyde
CAS No.	120743-99-9
Molecular Formula	C13H20O2Si
Molecular Weight	236.39 g/mol
Synonyms	4-(tert-Butyldimethylsilyloxy)benzaldehyde; p-((tert-Butyldimethylsilyl)oxy)benzaldehyde; 4-(TBDMSO)Benzaldehyde; 4-Hydroxybenzaldehyde TBDMS ether; 4-Formylphenyl tert-butyldimethylsilyl ether; Benzaldehyde, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 4-OTBDMS Benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-((tert-Butyldimethylsilyl)Oxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali and is easily oxidized; it is recommended to store under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.