Description

8-(Trifluoromethyl)Isoquinoline is a versatile fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl group, which is critical for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and metabolic stability.
• Material Science: Acts as a precursor for ligands in catalysis and for constructing organic electronic materials due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry to study protein-ligand interactions and improve pharmacokinetic properties.
• Fine Chemical Synthesis: A valuable starting material for synthesizing complex, fluorinated isoquinoline derivatives for various specialty chemical applications.

Basic Information

Product Name	8-(Trifluoromethyl)Isoquinoline
CAS No.	120568-10-7
Molecular Formula	C10H6F3N
Molecular Weight	197.16 g/mol
Synonyms	8-(Trifluoromethyl)isoquinoline; Isoquinoline, 8-(trifluoromethyl)-; 8-Trifluoromethylisoquinoline; 8-CF3-Isoquinoline; 1-Azanaphthalene, 8-(trifluoromethyl)-; 120568-10-7; 8-(Trifluoromethyl)-isoquinoline; 8-(Trifluoromethyl)isoquinoline (8-CF3-IQ)
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.