Description

2'-Fluoro-6'-Methoxyacetophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which serves as a critical precursor for the development of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Research: Used as a building block for developing new herbicides and pesticides with enhanced efficacy and selectivity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions, such as Suzuki and Heck reactions, to introduce the fluoromethoxyphenyl moiety into more complex molecular architectures.
• Fluorine Chemistry Research: A valuable substrate for studying the effects of fluorine substitution on the reactivity and physical properties of aromatic ketones.
• Material Science: Used in the development of specialty polymers and advanced materials where fluorine incorporation improves thermal stability and chemical resistance.

Basic Information

Product Name	2'-Fluoro-6'-Methoxyacetophenone
CAS No.	120484-50-6
Molecular Formula	C9H9FO2
Molecular Weight	168.16 g/mol
Synonyms	1-(2-Fluoro-6-methoxyphenyl)ethanone; 2-Fluoro-6-methoxyacetophenone; 2'-Fluoro-6'-methoxyacetophenone; Ethanone, 1-(2-fluoro-6-methoxyphenyl)-; 2-Fluoro-6-methoxy-1-acetylbenzene; 1-Acetyl-2-fluoro-6-methoxybenzene; 2-Fluoro-6-methoxyacetophenone; 2-Fluoro-6-methoxy phenyl methyl ketone
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-6'-Methoxyacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.