Description

[6Ar-[3(2E,4E),6Aalpha,10Abeta]]-5-(6A,7,10,10A-Tetrahydro-1-Hydroxy-6,6,9-Trimethyl-6H-Dibenzo[B,C]Pyran-3-Yl)-2,4-Pentadienoic Acid Methyl Ester is a high-purity synthetic cannabinoid derivative with a complex, defined stereochemistry. This compound is of significant interest as a key intermediate or reference standard in advanced pharmaceutical research and analytical chemistry. It is primarily required by research institutions, pharmaceutical R&D laboratories, and analytical service providers for method development, metabolic studies, and quality control of related active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block in the synthesis of novel cannabinoid receptor-targeted therapeutics.
• Analytical Reference Standard: Used for the identification, assay, and impurity profiling in HPLC, GC-MS, and LC-MS methods for cannabinoid-based compounds.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research to understand the biotransformation of related synthetic cannabinoids.
• Biochemical Research: Acts as a ligand or probe in in vitro studies investigating cannabinoid receptor (CB1/CB2) binding affinity and functional activity.
• Quality Control & Method Validation: Essential for calibrating instruments and validating analytical procedures in GMP/GLP-compliant environments.

Basic Information

Product Name	[6Ar-[3(2E,4E),6Aalpha,10Abeta]]-5-(6A,7,10,10A-Tetrahydro-1-Hydroxy-6,6,9-Trimethyl-6H-Dibenzo[B,C]Pyran-3-Yl)-2,4-Pentadienoic Acid Methyl Ester
CAS No.	120467-33-6
Molecular Formula	C25H30O4
Molecular Weight	394.51 g/mol
Synonyms	JWH-018 N-(5-Hydroxypentyl) Metabolite Methyl Ester; JWH-018 5-Hydroxypentyl Metabolite Methyl Ester; 1-Pentyl-3-(1-naphthoyl)indole 5-Hydroxypentyl Metabolite Methyl Ester; Methyl (2E,4E)-5-[1-hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydro-6H-benzo[c]chromen-3-yl]penta-2,4-dienoate; JWH 018 N-5-Hydroxypentyl Analog Methyl Ester; AM-2201 5-Hydroxypentyl Metabolite Methyl Ester (Related Structural Class)
EINECS	Contact for details

Quality Control

Our production of this high-grade synthetic intermediate adheres to strict in-process controls to ensure batch-to-batch consistency and structural integrity. Identity and purity are confirmed via advanced chromatographic and spectroscopic methods. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing specifications for identity, assay, and related substances. We support GMP/GLP-compliant research and can supply material suitable for use as a qualified reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.