Description

2-Trifluoroacetyl Vinyl Amine is a versatile fluorinated building block characterized by its reactive vinyl and trifluoroacetyl functional groups. This compound is essential for introducing the trifluoroacetyl moiety into complex molecular architectures, enabling the synthesis of advanced materials and active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the fluorine atoms confer improved biological activity and metabolic stability.
• Material Science: Serves as a monomer or precursor for fluorinated polymers and coatings, imparting desirable properties like chemical resistance and low surface energy.
• Organic Synthesis Building Block: Employed in various name reactions (e.g., Michael additions, cycloadditions) to construct complex heterocycles and functionalized molecules.
• Ligand and Catalyst Development: Useful for creating specialized ligands in coordination chemistry and catalysis research.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in organofluorine chemistry.

Basic Information

Product Name	2-Trifluoroacetyl Vinyl Amine
CAS No.	120417-45-0
Molecular Formula	C5H4F3NO
Molecular Weight	151.09 g/mol
Synonyms	N-Vinyl-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-vinylacetamide; 1-(Trifluoroacetyl)ethenamine; Vinyl trifluoroacetamide; Trifluoroacetic acid vinylamide; N-Ethenyl-2,2,2-trifluoroacetamide; TFVA
EINECS	Contact for details

Quality Control

Our 2-Trifluoroacetyl Vinyl Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.