Description

4-Butoxy-1,1,1-trifluoro-3-buten-2-one is a specialized fluorinated organic building block. This compound is valued for its unique reactivity profile, combining a trifluoromethyl ketone moiety with an alkoxy-substituted alkene, making it a versatile intermediate for synthesizing complex fluorinated molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications requiring the introduction of fluorine atoms to modulate the properties of target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where fluorination improves efficacy and environmental profile.
• Fluorinated Polymer Research: Serves as a monomer or modifier in the development of specialty polymers with unique surface, thermal, or chemical resistance properties.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated components for display technologies and organic semiconductors.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for cycloaddition reactions, nucleophilic additions, and other transformations to create complex fluoroorganic structures.
• Catalyst & Ligand Development: Acts as a precursor for creating novel fluorinated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	4-Butoxy-1,1,1-trifluoro-3-buten-2-one
CAS No.	120407-73-0
Molecular Formula	C8H11F3O2
Molecular Weight	196.17 g/mol
Synonyms	1,1,1-Trifluoro-4-butoxy-3-buten-2-one; 4-Butoxy-1,1,1-trifluorobut-3-en-2-one; 3-Buten-2-one, 4-butoxy-1,1,1-trifluoro-; Butyl 4,4,4-trifluoro-3-oxobut-1-enyl ether; 4-Butoxy-1,1,1-trifluoro-3-buten-2-one; TFBO (common abbreviation in research contexts)
EINECS	Contact for details

Quality Control

Our 4-Butoxy-1,1,1-trifluoro-3-buten-2-one is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance as a chemical intermediate. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its fluoride/strong alkali reactivity profile and high volatility, keep away from incompatible materials and ensure containers are properly sealed.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.