Description

Piperidine-3-Boronic Acid is a versatile and highly valuable boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery, catalyst development, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its ability to introduce the piperidine moiety into complex molecular structures.
• Suzuki-Miyaura Cross-Coupling: Serves as a pivotal boronic acid reagent for palladium-catalyzed cross-coupling reactions to create biaryl and heteroaryl compounds.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis and other catalytic processes.
• Material Science Research: Used in the creation of organic electronic materials, such as those for OLEDs and conductive polymers, where precise molecular architecture is required.
• Chemical Biology & Proteomics: Acts as a functional handle in the synthesis of chemical probes and inhibitors for studying enzyme function and protein interactions.

Basic Information

Product Name	Piperidine-3-Boronic Acid
CAS No.	120347-74-2
Molecular Formula	C5H12BNO2
Molecular Weight	128.97 g/mol
Synonyms	3-Piperidineboronic Acid; 3-Boronopiperidine; Piperidin-3-ylboronic Acid; 1-Azabicyclo[3.3.0]octan-3-ylboronic Acid (tautomer); 3-Pyridinylboronic Acid, hexahydro-; Boronic acid, B-(3-piperidinyl)-; (Piperidin-3-yl)boronic Acid
EINECS	Contact for details

Quality Control

Our Piperidine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' needs in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.