Description

Sodium Pentafluorobenzenesulfonate is a high-purity, organofluorine building block and reagent essential for advanced chemical synthesis. Its value lies in the unique reactivity imparted by the pentafluorophenylsulfonate (PFP-sulfonate) group, making it a superior leaving group in nucleophilic substitution reactions compared to traditional tosylates or mesylates. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecules, developing active ingredients, and creating novel fluorinated polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly where the introduction of fluorinated aromatic systems is required for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that benefit from the lipophilicity and stability of fluorinated aromatic rings.
• Polymer & Material Science: Serves as a monomer or functionalization agent in the production of specialty fluorinated polymers, coatings, and electronic materials with enhanced chemical resistance and thermal stability.
• Cross-Coupling Reactions: Acts as an effective electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for biaryl formation.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Derivatization Agent: Useful in analytical chemistry for derivatizing compounds to improve detection in techniques like HPLC or LC-MS.

Basic Information

Product Name	Sodium Pentafluorobenzenesulfonate
CAS No.	120193-44-4
Molecular Formula	C6F5SO3Na
Molecular Weight	264.10 g/mol
Synonyms	Pentafluorobenzenesulfonic Acid Sodium Salt; Sodium Pentafluorophenylsulfonate; PFP-Sulfonate Sodium Salt; Benzenesulfonic Acid, Pentafluoro-, Sodium Salt; Sodium 2,3,4,5,6-Pentafluorobenzenesulfonate; 2,3,4,5,6-Pentafluorobenzenesulfonic Acid Sodium Salt; Pentafluorophenyl Sulfonate Sodium Salt
EINECS	Contact for details

Quality Control

Every batch of Sodium Pentafluorobenzenesulfonate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters including assay (by HPLC or titration), identity confirmation (by IR and NMR), and levels of specific impurities. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.