Description

4'-Bromo-3'-(trifluoromethyl)acetophenone is a high-value brominated and fluorinated aromatic ketone building block. This compound matters for its unique molecular architecture, combining a reactive acetyl group with bromine and trifluoromethyl substituents, which is critical for introducing specific steric and electronic properties into target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of monomers and functional molecules for advanced polymers and liquid crystals.
• Chemical Biology Probes: Useful for constructing molecular probes to study enzyme mechanisms and protein interactions.

Basic Information

Product Name	4'-Bromo-3'-(Trifluoromethyl)Acetophenone
CAS No.	120077-70-5
Molecular Formula	C9H6BrF3O
Molecular Weight	267.05 g/mol
Synonyms	1-(4-Bromo-3-(trifluoromethyl)phenyl)ethan-1-one; 4'-Bromo-α,α,α-trifluoro-3'-methylacetophenone; 3'-Trifluoromethyl-4'-bromoacetophenone; 4-Bromo-3-trifluoromethylacetophenone; 1-Acetyl-4-bromo-3-trifluoromethylbenzene; 4-Bromo-α,α,α-trifluoro-m-acetophenone; p-Bromo-m-trifluoromethylacetophenone
EINECS	Contact for details

Quality Control

Our 4'-Bromo-3'-(trifluoromethyl)acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.