Description

6-Amino-2-Hydroxy-5-(Phenylsulfonyl)Nicotinonitrile is a high-value, multi-functional heterocyclic building block with a unique sulfonyl-substituted pyridine core. This compound matters for its role as a critical intermediate in the synthesis of complex pharmaceutical molecules and advanced organic materials. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Serves as a versatile precursor in the synthesis of novel herbicides, fungicides, and plant growth regulators with potential new modes of action.
• Material Science: Used in the research and development of organic semiconductors, liquid crystals, and photoactive materials due to its electron-withdrawing sulfonyl group and hydrogen-bonding capabilities.
• Chemical Synthesis Building Block: Provides a functionalized pyridine scaffold for further derivatization (e.g., amide formation, cyclization reactions) in custom synthesis and library production for high-throughput screening.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized colorants and fluorescent markers owing to its conjugated system and amino/hydroxy functional groups.

Basic Information

Product Name	6-Amino-2-Hydroxy-5-(Phenylsulfonyl)Nicotinonitrile
CAS No.	119672-36-5
Molecular Formula	C12H9N3O3S
Molecular Weight	275.28 g/mol
Synonyms	5-(Benzenesulfonyl)-6-amino-2-hydroxynicotinonitrile; 6-Amino-2-hydroxy-5-(phenylsulfonyl)pyridine-3-carbonitrile; 2-Hydroxy-6-amino-5-(phenylsulfonyl)-3-cyanopyridine; 3-Cyano-6-amino-2-hydroxy-5-(phenylsulfonyl)pyridine; 5-(Phenylsulfonyl)-6-amino-2-hydroxynicotinonitrile; 6-Amino-2-oxo-1,2-dihydro-5-(phenylsulfonyl)nicotinonitrile (Tautomeric form); 119672-36-5
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Hydroxy-5-(Phenylsulfonyl)Nicotinonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.