Description

3-Chloro-4-Ethoxy-1,1,1-Trifluoro-But-3-En-2-One is a high-value fluorinated organic building block characterized by its reactive enone and trifluoromethyl functionalities. This compound matters for its role as a versatile synthon in advanced organic synthesis, enabling the efficient introduction of fluorine atoms and complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in antiviral, anticancer, and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and coatings with unique surface properties.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring new fluorination methodologies and reaction pathways.
• Liquid Crystal & OLED Material Development: Used in the synthesis of fluorinated components for electronic display and lighting applications.

Basic Information

Product Name	3-Chloro-4-Ethoxy-1,1,1-Trifluoro-But-3-En-2-One
CAS No.	119577-49-0
Molecular Formula	C7H6ClF3O2
Molecular Weight	214.57 g/mol
Synonyms	3-Chloro-4-ethoxy-1,1,1-trifluorobut-3-en-2-one; 1,1,1-Trifluoro-3-chloro-4-ethoxy-3-buten-2-one; 3-Chloro-4-ethoxy-1,1,1-trifluorobut-3-en-2-one; 3-Buten-2-one, 3-chloro-4-ethoxy-1,1,1-trifluoro-; (E/Z)-3-Chloro-4-ethoxy-1,1,1-trifluorobut-3-en-2-one; Ethyl 3-chloro-4,4,4-trifluoroacetoacetate enol chloride derivative
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-4-Ethoxy-1,1,1-Trifluoro-But-3-En-2-One adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Ratio (GC)	Reported on COA
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.