Description

2-Butenenitrile, 2-(Ethylamino)-3-Hydroxy-, (Z)- (9Ci) is a specialized, high-purity nitrile derivative with a chiral hydroxy and aminoethyl substituent, making it a valuable chiral building block for advanced synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals where stereochemistry is critical. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced, stereoselective pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for enantioselective transformations.
• Fine Chemical Synthesis: Employed in the multistep synthesis of complex natural products and specialty materials.
• Bioconjugation Chemistry: Potential use in modifying biomolecules due to the reactivity of the nitrile and hydroxy groups.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	2-Butenenitrile, 2-(Ethylamino)-3-Hydroxy-, (Z)- (9Ci)
CAS No.	119520-30-8
Molecular Formula	C6H10N2O
Molecular Weight	126.16 g/mol
Synonyms	(Z)-2-(Ethylamino)-3-hydroxy-2-butenenitrile; 2-Butenenitrile, 2-(ethylamino)-3-hydroxy-, (Z)-; 3-Hydroxy-2-(ethylamino)-2-butenenitrile; (Z)-3-Hydroxy-2-(ethylamino)but-2-enenitrile; 2-(Ethylamino)-3-hydroxy-2-butenenitrile (Z-isomer); (2Z)-2-(Ethylamino)-3-hydroxybut-2-enenitrile
EINECS	Contact for details

Quality Control

Our 2-Butenenitrile, 2-(Ethylamino)-3-Hydroxy-, (Z)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (Z-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.