Description

3-(4-Fluoro-Phenyl)-Thiophene is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceuticals, agrochemicals, and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require fluorinated aromatic motifs for enhanced bioactivity and stability.
• Material Science: Serves as a monomer or precursor in the synthesis of conjugated polymers and organic semiconductors for electronic applications like OLEDs and OFETs.
• Ligand & Catalyst Development: Employed in the design of novel ligands for transition metal catalysis and organocatalysts, leveraging the electron-donating properties of the thiophene ring.
• Chemical Research: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fluorescent Probe Synthesis: Used as a core structure in the development of fluorescent dyes and molecular probes for bioimaging and diagnostic applications.

Basic Information

Product Name	3-(4-Fluoro-Phenyl)-Thiophene
CAS No.	119492-73-8
Molecular Formula	C10H7FS
Molecular Weight	178.23 g/mol
Synonyms	3-(4-Fluorophenyl)thiophene; 4-(3-Thienyl)fluorobenzene; 3-(p-Fluorophenyl)thiophene; 1-Fluoro-4-(thiophen-3-yl)benzene; Thiophene, 3-(4-fluorophenyl)-; 3-(4-Fluorophenyl)-1-thiophene; 3-(4-Fluorophenyl)thiofuran
EINECS	Contact for details

Quality Control

Our 3-(4-Fluoro-Phenyl)-Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO 9001 compliance for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.