Description

Cyclobutane, 1-Bromo-2-Methyl-, cis- (9Ci) is a specialized brominated cyclobutane derivative, a high-purity organic building block of significant interest in advanced synthetic chemistry. Its cis-configuration and reactive bromine substituent make it a valuable precursor for constructing complex, strained molecular architectures. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst development, and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for creating constrained ring systems.
• Agrochemical Synthesis: Used in the synthesis of advanced crop protection agents and herbicides, where the cyclobutane ring can impart unique biological activity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and advanced organic materials with specific structural properties.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways due to its ability to act as an alkylating agent.
• Academic and R&D Laboratories: A fundamental reagent for methodological studies in organic synthesis, including ring-opening and cross-coupling reactions.

Basic Information

Product Name	Cyclobutane, 1-Bromo-2-Methyl-, cis- (9Ci)
CAS No.	119404-66-9
Molecular Formula	C5H9Br
Molecular Weight	149.03 g/mol
Synonyms	cis-1-Bromo-2-methylcyclobutane; (1s,2s)-1-Bromo-2-methylcyclobutane; 1-Bromo-2-methyl-cis-cyclobutane; 2-Methyl-1-bromocyclobutane, cis-; Bromomethylcyclobutane (cis isomer); Cyclobutane, bromomethyl-, cis-
EINECS	Contact for details

Quality Control

Every batch of Cyclobutane, 1-Bromo-2-Methyl-, cis- (9Ci) is manufactured and analyzed under strict quality management protocols to ensure consistency and reliability for research and development purposes. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature and reactivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Isomeric Purity (cis-)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.