Description

4-(2-Nitro-Phenyl)-3-Oxo-Butyric Acid Methyl Ester is a specialized organic intermediate featuring a nitro-substituted aromatic ring and a β-keto ester functional group. This unique molecular architecture makes it a versatile and valuable building block in advanced organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs), particularly those requiring nitro-aromatic or β-keto ester motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where its structure can be incorporated into bioactive molecules.
• Organic Synthesis Building Block: Serves as a versatile reagent for Claisen condensations, Michael additions, and other carbon-carbon bond-forming reactions in fine chemical manufacturing.
• Dye and Pigment Research: Acts as an intermediate in the development of specialized nitro-aromatic dyes and organic pigments.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating novel polymers with specific optical or electronic properties.

Basic Information

Product Name	4-(2-Nitro-Phenyl)-3-Oxo-Butyric Acid Methyl Ester
CAS No.	119209-56-2
Molecular Formula	C11H11NO5
Molecular Weight	237.21 g/mol
Synonyms	Methyl 4-(2-nitrophenyl)-3-oxobutanoate; 3-Oxo-4-(2-nitrophenyl)butyric acid methyl ester; Methyl 3-oxo-4-(o-nitrophenyl)butyrate; 2-Nitrobenzylacetone methyl ester; 4-(2-Nitrophenyl)acetoacetic acid methyl ester; β-Keto ester intermediate; o-Nitrophenyl acetoacetate methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-(2-Nitro-Phenyl)-3-Oxo-Butyric Acid Methyl Ester adheres to stringent internal quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.