Description

3-Chloro-4,4,4-Trifluoro-2-Phenyl-But-2-Enal is a high-value, multi-functional chemical intermediate characterized by its unique trifluoromethyl and phenyl-substituted butenal structure. This compound is essential for synthesizing advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where its structural motifs confer desirable biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development teams in fine chemical and active pharmaceutical ingredient (API) manufacturing for constructing complex fluorinated target compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those incorporating trifluoromethyl groups to enhance potency, lipophilicity, and metabolic resistance.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Advanced Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer chains, altering surface properties, chemical resistance, and thermal stability.
• Organic Synthesis & Catalysis Research: A versatile reagent in academic and industrial laboratories for developing new synthetic methodologies, particularly in cross-coupling and cyclization reactions.

Basic Information

Product Name	3-Chloro-4,4,4-Trifluoro-2-Phenyl-But-2-Enal
CAS No.	119197-24-9
Molecular Formula	C10H6ClF3O
Molecular Weight	234.60 g/mol
Synonyms	3-Chloro-4,4,4-trifluoro-2-phenylbut-2-enal; 2-Butenal, 3-chloro-4,4,4-trifluoro-2-phenyl-; (E)-3-Chloro-4,4,4-trifluoro-2-phenylbut-2-enal; 3-Chloro-4,4,4-trifluoro-2-phenyl-2-butenal; α-(Chloromethylidene)-β,β,β-trifluorocinnamaldehyde
EINECS	Contact for details

Quality Control

Our 3-Chloro-4,4,4-Trifluoro-2-Phenyl-But-2-Enal is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.